Immunology/Autoimmune profile tests

AMA (antimitochondrial antibody)
This test is used when doctors are looking for evidence of primary biliary cirrhosis (PBC). This is because antimitochondrial antibodies are found in more than 90% of patients with this disease.

SMA (smooth muscle antibody)
This is a test that is used to detect autoimmune diseases such as autoimmune hepatitis (AIH). A liver biopsy is usually necessary to confirm the diagnosis and stage of the disease.

LKM (liver/kidney/microsomal antibody)
This test can be positive in a subtype of autoimmune hepatitis.